Complex Formation between Oligonucleotides and Polymers
نویسندگان
چکیده
منابع مشابه
Complex formation between oligonucleotides and polymers.
Both deoxyribonucleic and ribonucleic acids appear to possess a secondary structure, by virtue of the fact that the purine and pyrimidine bases can undergo hydrogen bonding with each other. In the case of DNA, this secondary structure takes the form of a long, highly ordered helix composed of two strands held to each other by hydrogen bonds between the bases (l-3). The secondary structure of RN...
متن کاملComplex Formation between Polycytidylic Acid and Guanine Oligonucleotides.
A study of the characteristics of the guanine-cytosine bond is important to the understanding of its contributions to the secondary structure of nucleic acids. However, such a study is very difficult to carry out with synthetic homopolymers because of the occurrence of stable self-bonded guanine structures (1). It is almost impossible to obtain polyriboguanylic acid (poly Gl) in a single-strand...
متن کاملMulticomponent complex formation between vinpocetine, cyclodextrins, tartaric acid and water-soluble polymers monitored by NMR and solubility studies.
This work deals with multicomponent complex formation of vinpocetine (VP) with beta-cyclodextrin (betaCD), sulfobutyl ether beta-cyclodextrin (SBEbetaCD) and tartaric acid (TA), in the presence or absence of water-soluble polymers, in aqueous solution. Complexation was monitored by phase-solubility and proton nuclear magnetic resonance ((1)H NMR) studies. TA demonstrated a synergistic effect on...
متن کاملPlasma can reduce Staphylococcus epidermidis biofilm formation on medical polymers
Medical polymers, such as urinary catheters are widely used biomaterials. One of the main problem for using the urinary catheters is biofilm formation on their surface, when they are used in a long time in the body. Virulence and pathogenicity of Staphylococcus epidermidis is often enhanced when growing as a biofilm. Many techniques have been presented to reduce the biofilm formation by surface...
متن کاملExperimental design, modeling and optimization of polyplex formation between DNA oligonucleotides and branched polyethylenimine.
The complexes formed by DNA and polycations have received great attention owing to their potential application in gene therapy. In this study, the binding efficiency between double-stranded oligonucleotides (dsDNA) and branched polyethylenimine (B-PEI) has been quantified by processing of the images captured from the gel electrophoresis assays. The central composite experimental design has been...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1961
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64320-0